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Hyaluronic acid/Sodium Hyaluronate

更新时间: 2024-04-29 23:29:10 责编:GHP038 浏览

Hyaluronic acid/Sodium Hyaluronate

Basic Information

Product Hyaluronic acid
Chemical Sodium Hyaluronate
Cas 9004-61-9
MF C14H22NNaO11
MW 403.31
Appearance White powder
Assay 50000Da
Package 1Kg/Foil Bag or 25Kg/Drum or As per your request
Storage Store in cool and dry places, keep away from strong light
Shelf life 2 years when properly stored


Mechanism of action

1) Percutaneous absorption
Skin model was used to test the percutaneous absorption of hydrolyzed sodium hyaluronate. The results showed that the percutaneous absorption rate of hydrolyzed sodium hyaluronate reached 36.2 % in 1 hour, 60.7 % in 8 hours and 69.5 % in 24 hours.

2) Scavenging free radicals
Hydrolyzed sodium hyaluronate can effectively eliminate reactive oxygen free radicals ( ROS ) induced by ultraviolet radiation, enhance cell antioxidant capacity and enhance skin's defense against ultraviolet radiation.

3) Repair damaged cells
hydrolyzed sodium hyaluronate can repair damaged cells and improve cell activity, thus reducing the damage of external environment to skin cells.

Specification

Items

Specifications

 

Cosmetic grade

sodium hyaluroate

(Lowest Molecular Weight )

Cosmetic grade

sodium hyaluroate

(Low Molecular Weight )

Cosmetic grade sodium hyaluroate

(Middle Molecular Weight )

Cosmetic grade

sodium hyaluroate

(High Molecular Weight )

Description

White powder

White powder

White powder

White powder

Particle size

100% pass through 80 mesh

100% pass through 80 mesh

100% pass through 80 mesh

100% pass through 80 mesh

PH

5.0-8.5

5.0-8.5

5.0-8.5

5.0-8.5

Transparency

≥99.0%

≥99.0%

≥99.0%

≥99.0%

Molecular Weight

2,000 Da - 8,000 Da

8,000 Da - 50,000 Da

1.0-1.5M Da.

≥1.8M Da

Loss on drying

≤8.0%

≤8.0%

≤8.0%

≤8.0%

Bulk Density

0.10-0.60g/cm3

0.10-0.60g/cm3

0.10-0.60g/cm3

0.10-0.60g/cm3

Protein

≤0.05%

≤0.05%

≤0.05%

≤0.05%

Heavy metals

≤10ppm

≤10ppm

≤10ppm

≤10ppm

Arsenic

≤2ppm

≤2ppm

≤2ppm

≤2ppm

Glucuronic acid

≥44%

≥44%

≥44%

≥44%

Sodium Hyaluronate

≥95%

≥95%

≥95%

≥95%

Bacteria counts

≤100cfu/g

≤100cfu/g

≤100cfu/g

≤100cfu/g

Mold & Yeast

≤10cfu/g

≤10cfu/g

≤10cfu/g

≤10cfu/g

E.Coli

Negative

Negative

Negative

Negative

S.Aureus

Negative

Negative

Negative

Negative

S.Apecies

Negative

Negative

Negative

Negative

 

Main efficacy
1) Deep moisturizing
Hydrolyzed sodium hyaluronate can be absorbed through skin, deeply moisturize skin, and increase skin moisture content. It can be used together with macromolecular sodium hyaluronate to achieve synergistic effect and better moisturizing effect.
2) Fade wrinkles
After 15 days, 30 days and 60 days of use, the average wrinkle depth ( sa ) of the hydrolyzed sodium hyaluronate group decreased by 16.0 %, 20.3 % and 25.6 % respectively.
3) Increase skin elasticity
Skin elasticity of the hydrolyzed sodium hyaluronate group increased 4.6 %, 5.2 % and 6.1 % respectively after 15 days, 30 days and 60 days of use. Long - term use of hydrolyzed sodium hyaluronate makes skin firm and elastic.
4) Clinical research
Dermatologists judge that after 30 days of use, 40 % of the subjects had significantly improved their wrinkles, while after 60 days of use, 60 % of the subjects had significantly reduced their wrinkles.

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